{"id":6578,"date":"2026-07-05T16:38:33","date_gmt":"2026-07-05T16:38:33","guid":{"rendered":"https:\/\/orlandorelocationreport.com\/?p=6578"},"modified":"2026-07-05T16:38:33","modified_gmt":"2026-07-05T16:38:33","slug":"this-plant-extract-can-make-a-lethal-drug-cocktail-can-it-also-treat-opioid-addiction","status":"publish","type":"post","link":"https:\/\/orlandorelocationreport.com\/?p=6578","title":{"rendered":"This plant extract can make a lethal drug cocktail. Can it also treat opioid addiction?"},"content":{"rendered":"
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By Karen Garcia, Los Angeles Times<\/strong><\/p>\n

LOS ANGELES \u2014 A plant extract that\u2019s gaining popularity as a pain cure-all and has been associated with multiple California deaths in its concentrated, synthetic form has been approved for research as a treatment for opioid addiction by the federal government.<\/p>\n

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Kratom is derived from the leaves of Mitragyna speciosa<\/em>, a tree native to Southeast Asia, and is commonly made into a powder or pill.<\/p>\n

Researchers say people in the U.S. are using kratom to alleviate anxiety, treat chronic pain or as a remedy for the symptoms associated with quitting opioids, due to its ability to bind with opioid receptors in the body. But recently, public health officials have raised alarms about a component of the leaf called 7-hydroxymitragynine, also known as 7-OH, an alkaloid that has the potential for abuse and addiction in high doses.<\/p>\n

Last year, the Los Angeles County Public Health Department linked the deaths of six county residents to the use of 7-OH mixed with other substances. The toxicology screens for some of the deceased revealed both kratom and 7-OH, leading to a countywide crackdown of products with either compound because they\u2019re unregulated.<\/p>\n

Although there is no scientific consensus on whether kratom has therapeutic value, the Food and Drug Administration has recommended that its potent 7-OH form be classified as a controlled substance. Consumers who use 7-OH as a pain reliever expecting an experience similar to consuming kratom are at risk, said Dr. Mason Turner, president-elect of the California Society of Addiction Medicine.<\/p>\n

\u201cI have a couple of patients that I work with who use 7-OH for chronic pain management, not realizing the potential of the medication, and then developed an opioid use disorder,\u201d Turner said. \u201cI think in that case it was very clear they were seeking it for the chronic pain, not to get high, not to have some kind of experience, but really to reduce their pain.\u201d<\/p>\n

About two decades ago, Turner said, the healthcare industry started acknowledging the limits and risks of prescribing opioids for chronic pain. Some doctors pulled back on prescriptions, recognizing the potential for abuse.<\/p>\n

<\/p>\n

That led some patients to find alternative solutions, he said.<\/p>\n

\u201cMaybe they don\u2019t get a good benefit, or maybe the benefit from some of the other treatments is not as robust as what they got from opioids,\u201d Turner said. \u201cSo they seek out some of these illicit products \u2026 or they look for kratom or 7-OH to be able to mitigate the pain.\u201d<\/p>\n

Turner said he supports further research into kratom and regulation because \u201cit could be worth exploring as a treatment for chronic pain.\u201d<\/p>\n

On June 1, the National Institutes of Health announced that researchers from the University of Florida would begin the first phase of clinical trials on kratom to evaluate it as a potential treatment for opioid addiction. The research would be done with the FDA\u2019s approval, according to officials.<\/p>\n

<\/p>\n

\u201cThis \u2026 is a major step toward expanding treatment options for the millions of Americans struggling with opioid use disorder, which has contributed to historically high overdose mortality rates,\u201d said Dr. Nora Volkow, director of NIH\u2019s National Institute on Drug Abuse, in a statement.<\/p>\n

Interest in kratom surged in the last couple of years as users have reported consuming the compound in the form of a pill, powder or tea to treat various ailments. A John Hopkins survey conducted in 2020 reported that 91% of respondents used kratom to treat chronic pain, 67% to treat anxiety, 64% for depression and 41% to treat opioid dependence.<\/p>\n

A more recent study by the University of Michigan and Texas State University found that more than 5 million people in the U.S., including more than 100,000 children ages 12 to 17, have used kratom, the compound experts say is growing in popularity with young adults.<\/p>\n

In the study, which analyzed data from the National Survey on Drug Use and Health collected between 2021 and 2024, researchers say that despite numerous state-level bans on kratom across the nation, its use is at an all-time high and is increasing.<\/p>\n

People between the ages of 21 and 34 said they used kratom at least once and 1% said they used it in the last year. The share of children ages 12 and older who said they had used kratom increased from 1.6% in 2021 to 1.9% in 2024.<\/p>\n

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The FDA has stated that neither kratom nor 7-OH are approved as drug products, dietary supplements or food additives, but that hasn\u2019t stopped storefronts and companies from selling them as such.<\/p>\n

Up until November you could find kratom and 7-OH products in smoke shops and specialty stores in California, but that has stopped.<\/p>\n

\u201cUntil kratom and its pharmacologically active key ingredients mitragynine and 7-OH are approved for use, they will remain classified as adulterants in drugs, dietary supplements and foods,\u201d the California Department of Public Health told The Times via email.<\/p>\n

In May, the California Department of Public Health and Atty. Gen. Rob Bonta filed a complaint against Ashlynn Marketing Group Inc., accusing the company of repeatedly flouting the state\u2019s regulations on kratom products.<\/p>\n

The filing, submitted in the San Diego County Superior Court, seeks a judge\u2019s order to condemn and destroy the embargoed kratom products, halt ongoing unlawful manufacturing and impose civil penalties.<\/p>\n

The California Department of Public Health \u201cis pursuing legal action because Ashlynn\u2019s continued manufacture and sale of these products pose a clear and preventable public\u2011health risk and violates state and federal law,\u201d said Dr. Erica Pan, the department\u2019s director and state public health officer. \u201c7-OH and kratom-derived products have been associated with addiction, serious health harms, overdose and death.\u201d<\/p>\n

The state is alleging its inspectors visited Ashlynn Marketing Group\u2019s facility in Santee in May 2025 and found kratom powders, capsules, liquids and chewable tablets being manufactured and held for sale.<\/p>\n

During the visit, inspectors issued an embargo to prohibit the sale and distribution of all kratom-related materials on-site, according to the complaint.<\/p>\n

Public health inspectors conducted follow-up visits at the facility in October and April, \u201ccollecting evidence at both inspections that indicated embargoed kratom products had been moved, tampered with and repackaged,\u201d according to public health officials.<\/p>\n

\u201cIn addition, investigators observed evidence of continued manufacturing and distribution of kratom materials,\u201d officials said. \u201cThe firm\u2019s owner continues to manufacture kratom products and ships orders weekly.\u201d<\/p>\n

To date, the California Department of Public Health has seized more than $5 million worth of kratom and 7-OH products, a spokesperson for the department told The Times.<\/p>\n

California and Los Angeles County are considering whether to tighten regulations or ban the compounds altogether.<\/p>\n

\u00a92026 Los Angeles Times. Visit at latimes.com. Distributed by Tribune Content Agency, LLC.<\/em><\/p>\n

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